Because of its antihistamine component, Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup should be used with caution in patients with a history of bronchial asthma, narrow angle glaucoma, gastrointestinal obstruction, or urinary bladder neck obstruction. Promethazine is in a class of medications called phenothiazines. Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Properly discard this product when it is expired or no longer needed. In children, excitement may occur first, and may be followed by: loss of coordination, drowsiness, loss of consciousness, seizures. Overdose: What Happens If I Take Too Much Promethazine DM? The cookie is used to store the user consent for the cookies in the category "Analytics". Many people using this medication do not have serious side effects.Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as confusion, hallucinations), shaking, trouble urinating, fast/slow/irregular heartbeat, seizure.A very serious allergic reaction to this drug is rare. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Drug class: Upper respiratory combinations. It blocks a natural substance in your body called histamine that normally causes allergy or common cold symptoms. It is often used in cough. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This interaction is more likely in certain predisposed patients only. Brompheniramine Maleate, Pseudoephedrine Hydrochloride, and Dextromethorphan Hydrobromide Syrup is a light pink-colored, clear grape-flavored syrup containing in each 5 mL (1 teaspoonful) brompheniramine maleate 2 mg, pseudoephedrine hydrochloride 30 mg and dextromethorphan hydrobromide 10 mg, available in the following sizes: Store at 20C to 25C (68F to 77F) [See USP Controlled Room Temperature]. Some products that may interact with this drug are: antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray), ketoconazole, levoketoconazole, rolapitant. Anticholinergic effects may be noted. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Examples of CYP2D6 inducers are: Promethazine DM also has other interactions that are unrelated to any enzyme. Consult your pharmacist or local waste disposal company. In children, excitement may occur first, and may be followed by loss of coordination, drowsiness, loss of consciousness, seizures. Don't take other medicines unless they've been discussed with your healthcare provider. Dosage form: syrup. BROMFED-DM Classification: Antihistamine + antitussive + sympathomimetic. All rights reserved. Hypersensitivity to any of the ingredients. It is often used in cough. Children may be more sensitive to the effects of antihistamines. If it is near the time of the next dose, skip the missed dose. The fluid will help loosen the mucus in your lungs. Symptoms of overdose may include: agitation, confusion, flushing, hallucinations, large pupils, muscle twitching, seizures. This combination medication is used to temporarily treat symptoms caused by the common cold, flu, allergies, or other breathing illnesses (such as sinusitis, bronchitis). Patient Drug Interactions Source: RxList 2023 RxList, Inc. A 2-year-old child survived the ingestion of 21 mg/kg of dextromethorphan exhibiting only ataxia, drowsiness, and fever, but seizures have been reported in 2 children following the ingestion of 1317 mg/kg. Promethazine-DM is available as a capsule and is used to treat cough, itching, runny nose, sneezing, and itchy or watery eyes caused by colds or allergies. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. Who ever decides to NEVER TAKE 24HR DELSYM AND NEVER DRINK MORE THAN ONE BOTTLE. If you have any of the following health problems, consult your doctor or pharmacist before using this medication: breathing problems (such as asthma, emphysema), diabetes, glaucoma, heart problems, high blood pressure, kidney problems, liver disease, seizures, stomach/intestinal problems (such as blockage, constipation, ulcers), overactive thyroid (hyperthyroidism), urination problems (such as trouble urinating due to enlarged prostate, urinary retention). However, Bromfed DM is FDA approved, and. Using these drugs along with this product could increase side effects (such as fast heartbeat, increased blood pressure, or drowsiness). It may contain 10% citric acid solution or 10% sodium citrate solution for pH adjustment. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Limit alcoholic beverages. Necessary cookies are absolutely essential for the website to function properly. Patients should be warned about engaging in activities requiring mental alertness, such as driving a car or operating dangerous machinery. 201.69, Pseudoephedrine Hydrochloride, USP (+)-Pseudoephedrine hydrochloride, Dextromethorphan Hydrobromide, USP 3-Methoxy-17-methyl-9, 13, 14 -morphinan hydrobromide monohydrate. Do not freeze liquid forms of this medication. Improper use of this medication (abuse) may result in serious harm (such as brain damage, seizure, death). To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. Treasure Island (FL): StatPearls. Discuss the risks and benefits with your doctor. Other adverse reactions may include: Dermatologic: Urticaria, drug rash, photosensitivity, pruritus. Interaction more likely in certain predisposed pts. 10 mg. Inactive Ingredients: sucrose, glycerin, ethyl alcohol, propylene glycol, methylparaben, citric acid, sodium citrate dihydrate, sodium benzoate, FD&C Red No. British Journal of Anaesthesia. Dextromethorphan may treat coughs because it is structurally related to certain types of opioids, like codeine. Antihistamines appear to compete with histamine for receptor sites on effector cells. Do clownfish have a skeleton or exoskeleton. Take this medication by mouth with or without food or as directed by your doctor. Out of these, the cookies that are categorized as necessary are stored on your browser as they are essential for the working of basic functionalities of the website. This drug may make you dizzy or drowsy or blur your vision. Keep your medications out of the reach of children and pets, ideally locked in a cabinet or closet. Do not use this product to treat cold symptoms in children younger than 6 years unless specifically directed by the doctor. You can use the study as a second opinion to make health care decisions. Symptoms of overdose may include: nausea, vomiting, loss of appetite, sweating, stomach/abdominal pain, extreme tiredness, agitation, confusion, flushing, hallucinations, yellowing eyes/skin, dark urine, seizures. Discard all unused and expired drugs but do not pour them down the drain or toilet. This drug may make you dizzy or drowsy or blur your vision. Take your next dose at the regular time. In this case, your healthcare provider may need to change the dose of your medicine to avoid any unwanted effects. These cookies track visitors across websites and collect information to provide customized ads. A dangerous drug interaction could occur. It's good to use if you have chest congestion and a cough. During pregnancy, this medication should be used only when clearly needed. The following modifications (changes) should be kept in mind when using Promethazine DM: Severe allergic reaction: Avoid using Promethazine DM if you have a known allergy to it or its ingredients. 40, and artificial grape flavor. The sooner that overdose symptoms are treated, the less likely complications will occur. 2005 - 2023 WebMD LLC. What Form (s) Does Promethazine-Dm Come In? What Are the Side Effects of Promethazine DM? Ask your doctor or pharmacist about using this product safely. Keep all medications away from children and pets. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. The study is based on brompheniramine maleate; dextromethorphan hydrobromide; pseudoephedrine hydrochloride and promethazine hydrochloride (the active ingredients of Bromfed-dm and Promethazine, respectively). If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Consult your doctor before breast-feeding. . Brompheniramine Maleate, USP . 7 Can you take bromfed DM if you have asthma? Drug interactions may change how your medications work or increase your risk for serious side effects. promethazine-dm oral , brompheniramine-pseudoephedrine oral Mechanism: unknown. Before taking this medicine. Precautions against aspiration must be taken, especially in infants and small children. C 16H 19BrN 2C 4H 4O 4 M.W. If your doctor has prescribed this medication, take it as directed. This is not a complete list of sideeffects, andothers may occur. Do not use this product to make a child sleepy. 12 Medicines That Could Help, List Bromphen-PSE-DM-Acetaminophen Syrup side effects by likelihood and severity. Who should not take BROMPHENIRAMINE-PSEUDOEPHED-DM? Avoid taking isocarboxazid, metaxalone, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, or tranylcypromine during treatment with this medication. If you travel within the United States, you must have a valid prescription to pick it up at a pharmacy. It has no analgesic or addictive properties. Betahistine is a vasodilator, a modest H 1 histamine agonist, and a powerful H 3 histamine receptor antagonist. for my read more. Monoamine oxidase inhibitors, opioid analgesics and serotonin toxicity. You can reduce the risk of constipation with a healthy diet consisting of ample fiber and water. Discuss the risks and benefits with your doctor. You may report side effects to Health Canada at 1-866-234-2345. Promethazine DM should be given to a pregnant person only if needed. Brompheniramine maleate is a histamine antagonist, specifically an H1-receptor-blocking agent belonging to the alkylamine class of antihistamines. Names. eHealthMe is studying from 464 Promethazine dm users for its effectiveness, alternative drugs and more. What conditions does Bromphen-PSE-DM-Acetaminophen Syrup treat. Naloxone hydrochloride 0.005 mg/kg intravenously may be of value in reversing the CNS depression that may occur from an overdose of dextromethorphan. Respiratory System: Tightness of chest and wheezing, shortness of breath. And check out drug take-back programs in your area. CNS: Disturbed coordination, tremor, irritability, insomnia, visual disturbances, weakness, nervousness, convulsions, headache, euphoria, and dysphoria. Make a copy of your Promethazine DM prescription, and if possible, keep your medication in its original container from your pharmacy with your name on the label. Of the two active ingredients, scientists are still learning how dextromethorphan treats coughs. Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms (such as drinking enough fluids, using a humidifier or saline nose drops/spray). Tell your doctor or pharmacist if you are taking other products that cause drowsiness such as opioid pain or cough relievers (such as codeine, hydrocodone), alcohol, marijuana (cannabis), drugs for sleep or anxiety (such as alprazolam, lorazepam, zolpidem), muscle relaxants (such as carisoprodol, cyclobenzaprine), or other antihistamines (such as cetirizine, diphenhydramine). PMID:31335081, Gillman PK. This medicine might contain phenylalanine (aspartame). . Oxygen, intravenous fluids, and other supportive measures should be employed as indicated. If you are taking the extended-release capsules, swallow them whole. Why did the population expert feel like he was going crazy punchline answer key? To stay healthy while youre not feeling well, it is essential to take Promethazine DM, as directed by your healthcare provider. 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